PNU109291
CAS No. : 187665-60-7
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| Cat. No. : | HY-103132 |
| M.Wt: | 409.52 |
| Formula: | C24H31N3O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
PNU109291 is a potent and selective 5-HT1D agonist. PNU109291 reduces dural plasma extravasation evoked by trigeminal ganglion stimulation[1].
In Vivo:PNU109291 (0.24, 2.4, 7.3, 24.4, 73.3 nmol/kg; s.c.) reduces dural plasma extravasation evoked by trigeminal ganglion stimulation in pigs[1].
PNU109291 (3 µM) inhibited evoked EPSCs (excitatory postsynaptic currents) in Freund's adjuvant (CFA) but not saline-injected rats[2].
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