Boc-Asp(OMe)-fluoromethyl ketone
CAS No. : 187389-53-3
(Synonyms: Boc-Asp(OMe)-FMK)
| Size | Price | Stock |
|---|---|---|
| 5mg | $131 | In-stock |
| 10mg | $204 | In-stock |
| 25mg | $450 | In-stock |
| 100mg | $932 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-103348 |
| M.Wt: | 263.26 |
| Formula: | C11H18FNO5 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Boc-Asp(OME)-Fluoromethyl Ketone is a broad range caspase inhibitor that inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8[1][2]. IC50 & Target: caspase[1][2] In Vitro: Boc-Asp(OME)-Fluoromethyl Keton (100 μM; 30 minutes; Polymorphonuclear leukocytes) prevents Fas-induced and spontaneous apoptosis ( CH-11)[1]. Boc-Asp(OME)-Fluoromethyl Keton (20 μM; 5 hours; J774.1/JA-4 cells) significantly increases LDH release[2].
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