CXCR2-IN-1
CAS No. : 1873376-49-8
| Size | Price | Stock |
|---|---|---|
| 1mg | $50 | In-stock |
| 5mg | $90 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $300 | In-stock |
| 50mg | $490 | In-stock |
| 100mg | $790 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-101022 |
| M.Wt: | 476.35 |
| Formula: | C19H20Cl2FN3O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 5.4 mg/mL (ultrasonic;warming) |
CXCR2-IN-1 is a central nervous system penetrant CXCR2 antagonist with a pIC50 of 9.3. IC50 & Target: pIC50: 9.3 (CXCR2)[1] In Vitro: CXCR2 plays an important role in the activation and recruitment of neutrophils to sites of inflammation. CXCR2-IN-1 (compound 22) shows favorable central nervous system penetration property (Br/Bl>0.45)[1]. In Vivo: CXCR2-IN-1 shows efficacy in a cuprizone-induced demyelination model through oral administration, providing evidence to support CXCR2 to be a potential therapeutic target to treat demyelinating diseases such as multiple sclerosis[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- CXCR2-IN-1
- Cat. No.:
- HY-101022
- Quantity:
Your information is safe with us.