PF-06733804


CAS No. : 1873373-33-1

1873373-33-1
Price and Availability of CAS No. : 1873373-33-1
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Cat. No. : HY-112434
M.Wt: 474.38
Formula: C20H19F5N4O4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1873373-33-1 :

PF-06733804 is a potent pan-Trk inhibitor in cell-based assays with IC50s of 8.4 nM, 6.2 nM and 2.2 nM for TrkA, TrkB and TrkC, respectively[1]. Anti-hyperalgesic effect[1]. In Vitro: PF-06733804 (Compound 19) also inhibits hERG in the FP and PX assay with IC50s of 79 μM and 88 μM, respectively[1].

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