N-Arachidonoyl-L-serine


CAS No. : 187224-29-9

(Synonyms: ARA-S)

187224-29-9
Price and Availability of CAS No. : 187224-29-9
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2.55 mM * 1 mL in Ethanol $110 Get quote
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Cat. No. : HY-120960
M.Wt: 391.54
Formula: C23H37NO4
Purity: >98 %
Solubility:
Introduction of 187224-29-9 :

N-Arachidonoyl-L-serine (ARA-S) is an endocannabinoid. N-Arachidonoyl-L-serine induces phosphorylation of Akt and MAPK in endothelial cells. N-Arachidonoyl-L-serine also induces endothelium-dependent vasodilation in isolated rat mesenteric and abdominal aortas. N-Arachidonoyl-L-serine exhibits neuroprotective effects after traumatic brain injury by reducing apoptosis. N-Arachidonoyl-L-serine promotes the opening of KV7.1/KCNE1 channels in mammalian cells and shortens the action potential duration in cardiomyocytes. N-Arachidonoyl-L-serine may be used in research on cardiovascular and cerebrovascular diseases and neurological disorders[1][2][3].

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