Ambroxol
CAS No. : 18683-91-5
(Synonyms: NA-872)
| Size | Price | Stock |
|---|---|---|
| 100mg | $50 | In-stock |
| 500mg | $80 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
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| Cat. No. : | HY-B1039 |
| M.Wt: | 378.10 |
| Formula: | C13H18Br2N2O |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 200 mg/mL |
Ambroxol (NA-872), an active metabolite of the prodrug Bromhexine, has potent expectorant effects. Ambroxol is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research[1][2]. In Vivo: Ambroxol (NA-872; 1, 3, 4, 5 mM for 12 consecutive days in drinking water) results in increased brain glucocerebrosidase activity in wild-type mice, transgenic mice expressing the heterozygous L444P mutation in the murine glucocerebrosidase 1 gene, and transgenic mice overexpressing human α-synuclein[2].
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