ML 10302 (hydrochloride)


CAS No. : 186826-17-5

186826-17-5
Price and Availability of CAS No. : 186826-17-5
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5mg $120 Get quote
10mg $170 Get quote
25mg $335 Get quote
50mg $490 Get quote
100mg $690 Get quote
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Cat. No. : HY-14442
M.Wt: 349.25
Formula: C15H22Cl2N2O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 186826-17-5 :

ML 10302 hydrochloride is a potent and selective 5-HT4 receptor agonist, with an EC50 of 4 nM. ML 10302 hydrochloride displays more than 680-fold selectivity over 5-HT3 receptor in binding assay[1][2]. IC50 & Target: EC50: 4 nM (5-HT4 receptor)[1] In Vitro: ML 10302 hydrochloride shows Kis of 1.07 nM and 782 nM for 5-HT4 receptor and 5-HT3 receptor, respectively, in binding assay[1].
In Vivo: ML 10302 hydrochloride (20?mg/kg; s.c.) induces the soluble form of amyloid precursor protein (sAPPα) production in the cortex of mice[3].

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