(Rac)-Roscovitine


CAS No. : 186692-44-4

(Synonyms: (Rac)-Seliciclib; (Rac)-CYC202)

186692-44-4
Price and Availability of CAS No. : 186692-44-4
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Cat. No. : HY-50892
M.Wt: 354.45
Formula: C19H26N6O
Purity: >98 %
Solubility:
Introduction of 186692-44-4 :

(Rac)-Roscovitine ((Rac)-Seliciclib) is a selective cyclin-dependent kinases (CDKs) inhibitor. (Rac)-Roscovitine binds to the active sites of CDKs competitively with ATP, inhibiting the phosphorylation activity of CDKs. (Rac)-Roscovitine induces apoptosis in cancer cells. (Rac)-Roscovitine is promising for research of cancers or other diseases associated with CDK dysregulation, such as neurodegenerative diseases, cardiac disorders, viral and protozoan infections, glomerulonephritis, and chronic inflammation[1].

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