4-Bromo-1H-indazole


CAS No. : 186407-74-9

186407-74-9
Price and Availability of CAS No. : 186407-74-9
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Cat. No. : HY-69085
M.Wt: 197.03
Formula: C7H5BrN2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 186407-74-9 :

4-Bromo-1H-indazole is a carbonic anhydrase inhibitor, with an IC50 of 0.403 mM and a Ki of 0.383 mM against hCA-I, as well as an IC50 of 0.700 mM and a Ki of 0.935 mM against hCA-II. 4-Bromo-1H-indazole reduces the catalytic activity of human I and II isoforms of carbonic anhydrase[1]. In Vitro:4-Bromo-1H-indazole inhibits purified human erythrocyte carbonic anhydrase I and II via non-competitive inhibition[1].

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