Salbutamol


CAS No. : 18559-94-9

(Synonyms: Albuterol; AH-3365)

18559-94-9
Price and Availability of CAS No. : 18559-94-9
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250mg $75 In-stock
500mg $100 In-stock
1g $135 In-stock
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Cat. No. : HY-B1037
M.Wt: 239.31
Formula: C13H21NO3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 18559-94-9 :

Salbutamol (Albuterol) is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease[1][2]. In Vitro:Salbutamol (16 μM; 24 h) significantly induces EMT, migration and invasion by ERK (extracellular signal-regulated kinase) phosphorylation in gastric cancer cells[1].
In Vivo:Salbutamol (5 mg/kg; oral administration; 2 weeks) can increase tumor growth in nude mice with gastric cancer[1].
Salbutamol (6 mg/kg; oral administration; 4 weeks) has a significant protective effect against Streptozotocin (HY-13753)-induced skeletal muscle atrophy in diabetic rats[2].

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