3PO
CAS No. : 18550-98-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $66 | In-stock |
| 10mg | $92 | In-stock |
| 25mg | $167 | In-stock |
| 50mg | $251 | In-stock |
| 100mg | $436 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-19824 |
| M.Wt: | 210.23 |
| Formula: | C13H10N2O |
| Purity: | >98 % |
| Solubility: | DMSO : 60 mg/mL (ultrasonic) |
3PO is an inhibitor of PFKFB3. 3PO attenuates the proliferation of several cancer cell lines with IC50s of 1.4-24 μmol/L. 3PO suppresses glucose uptake and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+ and NADH. 3PO can be used for the research of cancer[1]. In Vitro:3PO (0-33 μM; 0-36 h) inhibits Jurkat cells proliferation by influence cell cycle[1]. 3PO (10 μM/L; 0-36 h) suppresses glycolytic flux to lactate in Jurkat cells[1]. 3PO (10 μM/L; 0-36 h) inhibits cellular proliferation of transformed tumor cell lines[1]. In Vivo:3PO (0.07 mg/g; i.p. once per day for 14 days) inhibits the growth of Lewis lung carcinoma xenografts in C57Bl/6 mice[1]. 3PO (0.07 mg/g; i.p. three sequential daily injections followed by 3 off days for 14 days) inhibits the tumor growth in BALB/c athymic mice[1]. 3PO (0.07 mg/g; i.p. two daily injections followed a 7-day rest for 14 days) inhibits the tumor growth in BALB/c athymic mice[1]. 3PO (0.07 mg/g; i.p. once) inhibits Fru-2,6-BP and glucose uptake in C57Bl/6 mice[1].
Your information is safe with us.