PF-06761281
CAS No. : 1854061-19-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $180 | In-stock |
| 25mg | $400 | In-stock |
| 50mg | $700 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
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| Cat. No. : | HY-120669 |
| M.Wt: | 283.28 |
| Formula: | C13H17NO6 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 50 mg/mL |
PF-06761281 (Compound 4a) is a potent, orally active, partial selective sodium-coupled citrate transporter (NaCT or SLC13A5) inhibitor with IC50 values of 0.51, 13.2 and 14.1 µM against HEKNaCT, HEKNaDC1 and HEKNaDC3, respectively[1]. IC50 & Target: IC50: 0.51 µM (HEKNaCT), 13.2 µM (HEKNaDC1), 14.1 µM (HEKNaDC3)[1] In Vitro: PF-06761281 (Compound 4a) inhibits citrate uptake with IC50 values of 0.12, 0.21 and 0.74 µM in rat, mouse and human Heps[1].
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