GR-46611
CAS No. : 185259-85-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $57 | In-stock |
| 5mg | $105 | In-stock |
| 10mg | $170 | In-stock |
| 25mg | $340 | In-stock |
| 50mg | $540 | In-stock |
| 100mg | $728 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-101248 |
| M.Wt: | 377.48 |
| Formula: | C23H27N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C) |
GR-46611 is a 5-HT1D receptor agonist. GR-46611 can be used in the research of bladder hyperactivity, leukemia[1][3].
In Vitro:GR-46611 (1 μM, 48 h) induces CEM cell proliferation[2].
In Vivo:GR-46611 (1 mg/kg, i.p. ) significantly improves survival of Dravet syndrome (DS) mice[1].
GR-46611 (0.03-300 μg/kg, i.v.) increases threshold volume, bladder capacity, and residual volume in chronic spinal cord injury (SCI) cats[3].
GR46611 (3-30 mg/kg, s.c.) causes a dose-related decrease in rectal temperature in the adult guinea-pig[4].
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