Butabindide (oxalate)


CAS No. : 185213-03-0

(Synonyms: UCL-1397 (oxalate))

185213-03-0
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5mg $180 In-stock
10mg $300 In-stock
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Cat. No. : HY-107759
M.Wt: 393.43
Formula: C19H27N3O6
Purity: >98 %
Solubility: H2O : 39 mg/mL (ultrasonic;warming)
Introduction of 185213-03-0 :

Butabindide (UCL-1397) oxalate is a potent, selective tripeptidvl peptidase II (TPP II) inhibitor with Ki values of 7 nM and 10 μM for TPP II and TPP I, respectively. Butabindide oxalate inhibits TPP II to protect CCK-8 against inactivation[1][2]. IC50 & Target:IC50: 7 nM (TPP II) and 10 μM (TPP I)[1] In Vitro:Butabindide (UCL-1397; 0-24 nM; membranes of rat cerebral cortex) oxalate inhibits TPP II activity of cerebral membranes[2]. In Vivo:Butabindide (UCL-1397; 10 mg/kg; i.v.; for 20 min) oxalate inhibits the breakdown of CCK-8 in the gastrointestinal tract and increases satiety in mice[2].

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