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|---|---|---|
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| 250 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-14542C |
| M.Wt: | 509.04 |
| Formula: | C22H25ClN4O4S2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Ziprasidone (CP-88059) mesylate is an orally active combined 5-HT and dopamine receptor antagonist[1]. Ziprasidone mesylate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM)[1]. In Vitro: Ziprasidone mesylate (0-500 nM, 150 seconds) blocks wild-type hERG current[2]. In Vivo: Ziprasidone mesylate (oral gavage; 20 mg/kg; once daily; 7 weeks) results in weight loss, low level physical activity, high resting energy expenditure and greater capacity for thermogenesis when subjected to cold[3].
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