GSK2188764
CAS No. : 1849587-68-3
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| Cat. No. : | HY-120808 |
| M.Wt: | 391.26 |
| Formula: | C17H16Cl2N6O |
| Purity: | >98 % |
| Solubility: |
GSK2188764 is a Toxoplasma gondii rhoptry protein 18 (ROP18) inhibitor with reported IC50 values of 7.49 μM against Toxoplasma gondii. GSK2188764 inhibits serine-threonine kinase activity of ROP18 in vitro.GSK2188764 can be used for the research of toxoplasmosis[1]. In Vitro:GSK2188764 (up to 10 μM; 10 min pre-incubation, 3 h reaction) weakly inhibits recombinant Toxoplasma gondii ROP18 kinase activity in vitro, with an IC50 of 7.49 μM against the FL-E substrate and >10 μM against the FL-T and FL-8 substrates[1].
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