GSK2226649A
CAS No. : 1848232-20-1
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| Cat. No. : | HY-103074 |
| M.Wt: | 378.81 |
| Formula: | C15H12ClFN6OS |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
GSK2226649A (compound 2) is a novel activator of satellite cell proliferation and enhanced repair of damaged muscle[1].
In Vitro:GSK2226649A (compound 2) (0.1-10μM) can dose-dependently promote the proliferation of muscle stem cells, and can effectively accelerate the repair of damaged skeletal muscle in an in vivo mouse model of skeletal muscle injury[1].
In Vivo:The pharmacokinetic parameters of GSK2226649A(compound 2) in mice
| Dose(mg) | route | Cmax(ng/mL) | Tmax(hrs) | T1/2(hrs) | AUC0-inf(h*ng/mL) |
| 30 | oral | 1384 | 0.5 | 1.6 | 1720 |
| 30 | SC | 1783 | 1.0 | 6.1 | 12077 |
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- Cat. No.:
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