CM-272 (Standard)
CAS No. : 1846570-31-7
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| Cat. No. : | HY-101925R |
| M.Wt: | 478.63 |
| Formula: | C28H38N4O3 |
| Purity: | >98 % |
| Solubility: |
CM-272 (Standard) is the analytical standard of CM-272 (HY-101925). This product is intended for research and analytical applications. CM-272 is a first-in-class, potent, selective, substrate-competitive and reversible dual G9a/DNA methyltransferases (DNMTs) inhibitor with antitumor activities. CM-272 inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP with IC50s of 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing IFN-stimulated genes and immunogenic cell death[1].
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- CM-272 (Standard)
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- HY-101925R
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