Ethacridine (lactate)
CAS No. : 1837-57-6
(Synonyms: Acrinol)
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| Cat. No. : | HY-B2174 |
| M.Wt: | 343.38 |
| Formula: | C18H21N3O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic);H2O : 12.5 mg/mL (ultrasonic) |
Ethacridine lactate (Acrinol) is a widely used antiseptic and abortifacient. Ethacridine lactate is effective against Staphylococcus aureus and other gram-positive cocci. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor[1][2][3]. IC50 & Target: poly(ADP-ribose) glycohydrolase (PARG)[2] In Vitro: Acrinol is effective against S. aureus including MRSA, with the MICs ranging from 100-200 μg/mL. The MIC of Acrinol for Eschericia coli is 200-800 μg/mL, and it is over 1,600 μg/mL for Proteus vulgaris and Proteus mirabilis[3]. In Vivo: Ethacridine lactate can be used for termination of pregnancy[1].
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