HLF1-11
CAS No. : 183623-03-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $60 | In-stock |
| 10mg | $100 | In-stock |
| 25mg | $200 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-106228 |
| M.Wt: | 1374.58 |
| Formula: | C56H95N25O14S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
HLF1-11, a human lactoferrin-derived peptide, is a broad spectrum antimicrobial agent. HLF1-11 inhibits human MPO activity. HLF1-11 also directs GM-CSF-driven monocyte differentiation toward macrophages, and enhances immune responses[1][2].
In Vitro: hLF1-11 (1, 10, and 100 μg/mL) directs differentiation of monocytes toward a macrophage subset during granulocyte-macrophage colony-stimulating factor (GM-CSF)-driven monocytes differentiation[2].
hLF1-11 (0.5-250 μg/mL) inhibits human MPO activity[3].
hLF1-11 (100 μg/mL, 90 min) inhibits ROS induction induced by LPS in monocytes[3].
hLF1-11 (8-34 μΜ, 2 h) is active against fluconazole-resistant C. albicans[5].
In Vivo: hLF1-11 (20 mg/kg, injected into the debrided tibial cavity) shows ability against MRSA osteomyelitis in rabbits[4].
hLF1-11 (40 μg/kg, i.v.) is active against C. albicans-infected mice[6].
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- Cat. No.:
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