(S,R,S)-AHPC-PEG6-C4-Cl


CAS No. : 1835705-59-3

(Synonyms: VH032-PEG6-C4-Cl; VHL Ligand-Linker Conjugates 10; E3 ligase Ligand-Linker Conjugates 9)

1835705-59-3
Price and Availability of CAS No. : 1835705-59-3
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50mg $344 In-stock
100mg $550 In-stock
500mg $1950 In-stock
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Cat. No. : HY-103606
M.Wt: 827.47
Formula: C40H63ClN4O10S
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL;Ethanol : 100 mg/mL (ultrasonic)
Introduction of 1835705-59-3 :

(S,R,S)-AHPC-PEG6-C4-Cl is a conjugate of ligands for E3 and 25-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-PEG6-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1]. In Vitro: HaloPROTACs are designed to induce ubiquitylation and degradation of HaloTag7 fusion proteins[1].

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