CAS No. : 1835705-59-3
(Synonyms: VH032-PEG6-C4-Cl; VHL Ligand-Linker Conjugates 10; E3 ligase Ligand-Linker Conjugates 9)
| Size | Price | Stock |
|---|---|---|
| 50mg | $344 | In-stock |
| 100mg | $550 | In-stock |
| 500mg | $1950 | In-stock |
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| Cat. No. : | HY-103606 |
| M.Wt: | 827.47 |
| Formula: | C40H63ClN4O10S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;Ethanol : 100 mg/mL (ultrasonic) |
(S,R,S)-AHPC-PEG6-C4-Cl is a conjugate of ligands for E3 and 25-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-PEG6-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1]. In Vitro: HaloPROTACs are designed to induce ubiquitylation and degradation of HaloTag7 fusion proteins[1].
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