Boc-C1-PEG2-C4-Cl
CAS No. : 1835705-53-7
(Synonyms: PROTAC Linker 1)
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|---|---|---|
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| Cat. No. : | HY-108371 |
| M.Wt: | 294.81 |
| Formula: | C14H27ClO4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL |
Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. In Vitro: PROTAC technology employs small molecules that recruit target proteins for ubiquitination and removal by the proteasome. The synthesis of PROTAC compounds that mediate the degradation of c-ABL and BCR-ABL by recruiting either Cereblon or Von Hippel Lindau E3 ligases is reported. Boc-C1-PEG2-C4-Cl is designated as 6-2-2[1].
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