17(S)-HETE
CAS No. : 183509-25-3
| Size | Price | Stock |
|---|---|---|
| 10μg | $305 | Get quote |
| 25μg | $612 | Get quote |
| 50μg | $980 | Get quote |
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| Cat. No. : | HY-116050 |
| M.Wt: | 320.47 |
| Formula: | C20H32O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
17S-HETE is arachidonic acid metabolite through cytochrome P-450 pathways. 17S-HETE serves as allosteric activator of the cytochrome P450 1B1 and inhibitor of ATPase, induces cardic hypertrophy[1][2].
In Vitro:17S-HETE (5-20 μM) promotes the development of cardiac hypertrophy in human, through increasing CY1B1 at activity and protein levels[1].
In Vivo:17S-HETE (1-20 μg, i.a.) inhibits proximal tubule ATPase activity in New Zealand white rabbit[2].
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