Desmethyl Erlotinib (hydrochloride)
CAS No. : 183320-51-6
(Synonyms: OSI-420; CP-373420 (hydrochloride))
| Size | Price | Stock |
|---|---|---|
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| 10mg | $252 | In-stock |
| 50mg | $642 | In-stock |
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| Cat. No. : | HY-13256 |
| M.Wt: | 415.87 |
| Formula: | C21H22ClN3O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Desmethyl Erlotinib hydrochloride (OSI-420) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor[1]. Desmethyl Erlotinib (hydrochloride) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vivo: Desmethyl Erlotinib exhibits t1/2 of 11.96±2.01 h in a pharmacokinetic study in Wistar rats[1].
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