Tipiracil
CAS No. : 183204-74-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $54 | In-stock |
| 10mg | $82 | In-stock |
| 25mg | $126 | In-stock |
| 50mg | $165 | In-stock |
| 100mg | $219 | In-stock |
| 200mg | $284 | In-stock |
| 500 mg | Get quote | |
| 1 g | Get quote | |
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| Cat. No. : | HY-A0063A |
| M.Wt: | 242.66 |
| Formula: | C9H11ClN4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 1 mg/mL (ultrasonic;warming);H2O : 1 mg/mL (ultrasonic) |
Tipiracil is a thymidine phosphorylase (TPase) inhibitor. IC50 & Target: thymidine phosphorylase[1] In Vitro: Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil increases trifluridine exposure by inhibiting its metabolism by thymidine phosphorylase. The combination of Trifluridine and Tipiracil is a new oral treatment for metastatic colorectal cancer[2]. Tipiracil prevents degradation of FTD through a first-pass effect as a thymidine phosphorylase inhibitor[3].
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