Cabazitaxel
CAS No. : 183133-96-2
(Synonyms: XRP6258; RPR-116258A; taxoid XRP6258)
| Size | Price | Stock |
|---|---|---|
| 5mg | $35 | In-stock |
| 10mg | $55 | In-stock |
| 25mg | $77 | In-stock |
| 50mg | $88 | In-stock |
| 100mg | $165 | In-stock |
| 500mg | $495 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
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| Cat. No. : | HY-15459 |
| M.Wt: | 835.93 |
| Formula: | C45H57NO14 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. In Vitro: The cytotoxicity of cabazitaxel (100 μg/mL) on 4T1 cells without irradiation is 70.8%. Cabazitaxel (100 μg/mL) exhibits a concentration-dependent antiproliferation effect, with the antiproliferative activity of 56.2%[1]. In Vivo: Cabazitaxel (10 mg/kg, i.v.) has certain toxicity to liver and kidney but it can be avoided by integrated into Ans. The body weights of mice treated with AN-ICG-CBX and AN-CBX have a slightly decrease, while body weights of the free CBX group significantly decrease compared to the control group[1].
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