iJak-381
CAS No. : 1831144-46-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $289 | In-stock |
| 10mg | $500 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-125019 |
| M.Wt: | 612.03 |
| Formula: | C28H28ClF2N9O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
iJak-381 is a JAK1/2 inhibitor with anti-inflammatory activity. iJak-381 blocks IL-13 signaling and also inhibits IL-4 and IL-6 signaling pathways. iJak-381 also reduced p-STAT6 levels and inhibited the influx of inflammatory cells into the lungs of mice. iJak-381 inhibits airway hyperresponsiveness (AHR)[1]. IC50 & Target:STAT6; JAK1; JAK2[1]
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