YM116
CAS No. : 183012-13-7
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| Cat. No. : | HY-120067 |
| M.Wt: | 247.29 |
| Formula: | C16H13N3 |
| Purity: | >98 % |
| Solubility: |
YM116 is an orally active and competitive CYP17A1 (17,20-lyase) inhibitor (Ki: 0.38 nM). YM116 reduces the synthesis of adrenal androgens by preferentially inhibiting C17-20 lyase activity. YM116 decreases the serum testosterone concentration, reduces dehydroepiandrosterone sulfate levels and decreases prostatic weights[1][2].
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