Valepotriate
CAS No. : 18296-44-1
(Synonyms: Valtrate)
| Size | Price | Stock |
|---|---|---|
| 1mg | $94 | In-stock |
| 5mg | $198 | In-stock |
| 10mg | $336 | In-stock |
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| Cat. No. : | HY-N0718 |
| M.Wt: | 422.47 |
| Formula: | C22H30O8 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Valepotriate can be isolated from?Valeriana jatamansi?Jones, has anti-epileptic and anti-cancer activities[1][2]. In Vivo:Valepotriate?showed significant anti-epileptic activity against MES- and PTZ-induced epilepsy at doses of 5, 10, and 20 mg/kg, and ED50?values for MES- and PTZ-induced epilepsy were 7.84 and 7.19 mg/kg, respectively. Furthermore,?valepotriate?(10 and 20 mg/kg) can significantly prolong sleeping time and shorten the latency time on the pentobarbital sodium-induced sleeping time test. Furthermore,?valepotriate?(5, 10, and 20 mg/kg) could significantly up-regulate the expression of GABAA, GAD65, and Bcl-2 and down-regulate the expression of caspase-3, but had no significant effect on the expression of GABAB[2].
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