ML404
CAS No. : 1826026-00-9
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| Cat. No. : | HY-114898 |
| M.Wt: | 328.75 |
| Formula: | C17H13ClN2O3 |
| Purity: | >98 % |
| Solubility: |
ML404 (Compound 38) is an inhibitor of the mitochondrial permeability transition pore (mtPTP), which can suppress mitochondrial swelling (EC50=4.9 nM) and only disrupts mitochondrial coupling (an adverse effect) at concentrations > 100 μM. ML404 can be utilized in research related to multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), muscular dystrophies (MD), myocardial infarction, and stroke[1].
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