AZ0108
CAS No. : 1825345-52-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $556 | Get quote |
| 10mg | $890 | Get quote |
| 25mg | $1780 | Get quote |
| 50 mg | Get quote | |
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| Cat. No. : | HY-100847 |
| M.Wt: | 500.45 |
| Formula: | C24H20F4N6O2 |
| Purity: | >98 % |
| Solubility: |
AZ0108 is an inhibitor for poly ADP-ribose polymerase (PARP), which inhibits PARP1, PARP2, PARP3, PARP6, TNKS1, TNKS2, with IC50s of <0.03, <0.03, 2.8, 0.083, 3.2, >3 μM, respectively. AZ0108 prevents centrosome clustering with an EC50 of 0.053 μM, and exhibits cytotoxicity in cell OCI-LY-19 with GI50 of 0.017 μM. AZ0108 exhibits good in vivo pharmacokinetic characters in rat/mouse models[1].
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