SGC2085
CAS No. : 1821908-48-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $290 | In-stock |
| 10mg | $440 | In-stock |
| 50mg | $1250 | In-stock |
| 100mg | $1750 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-100565 |
| M.Wt: | 312.41 |
| Formula: | C19H24N2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
SGC2085 is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC50 of 50 nM. SGC2085 also selectively inhibits PRMT6 with an IC50 value of 5.2 μM, but not other PRMT proteins[1].
IC50 & Target:IC50: 50 nM (CARM1)[1]
In Vitro:SGC2085 (1 μM, 10 μM, 50 μM; 48 h) is fully selective for 21 human protein methyltransferases[1].
SGC2085 (10 μM; 48 h) exhibits low cell permeability and no cell activity in HEK293 cells[1].
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