Exatecan Intermediate 2


CAS No. : 182182-31-6

182182-31-6
Price and Availability of CAS No. : 182182-31-6
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250mg $40 In-stock
1g $71 In-stock
5g $262 In-stock
10g $420 In-stock
25g $840 In-stock
100g $2491 In-stock
500g $8333 In-stock
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Cat. No. : HY-W021377
M.Wt: 250.27
Formula: C13H15FN2O2
Purity: >98 %
Solubility: DMSO : 55 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic)
Introduction of 182182-31-6 :

Exatecan Intermediate 2 (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers[1]. In Vitro:Camptothecin derivatives are a class of cytotoxic small molecules that can be used in the preparation of antibody-drug conjugates. Camptothecin derivatives generally exhibit antitumor effects by inhibiting topoisomerase I[1].

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