Indolelactic acid
CAS No. : 1821-52-9
(Synonyms: Indole-3-lactic acid)
| Size | Price | Stock |
|---|---|---|
| 100mg | $90 | In-stock |
| 250mg | $207 | In-stock |
| 1g | $393 | In-stock |
| 5g | $1371 | In-stock |
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| Cat. No. : | HY-113099 |
| M.Wt: | 205.21 |
| Formula: | C11H11NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Indolelactic acid (Indole-3-lactic acid) is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures. Indolelactic acid has anti-inflammation and potential anti-viral activity[1][3][4].
In Vitro:Indolelactic acid (1 mM, 5 days) upregulates CXCR3, granzyme B, and immunoregulatory galectin-1 in Th2 cells[2].
Indolelactic acid (0.1-10 mM, 1 h) significantly inhibits LPS-induced inflammation in RAW blue macrophages and Caco-2 cells[3].
Indolelactic acid (0.1-10 mM, 1 h) inhibits TNF-α induced inflammation in HT-29 cells[3].
Indolelactic acid (10 mM, 1 h) activates the AhR and downstream Nrf2 pathway in Caco-2 cells[3].
Indolelactic acid (5 μM, 24 h) enhances the IFIT2 and RSAD2 mRNA expression in H4 cells stimulated by IL-1β[4].
In Vivo:Indolelactic acid (gavage feeding, 10 μM, 5 μL, 5 days, C57BL/6 mice) benefits the immature intestine preferentially[4].
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