IRAK4-IN-1
CAS No. : 1820787-94-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $190 | In-stock |
| 10mg | $290 | In-stock |
| 25mg | $590 | In-stock |
| 50mg | $870 | In-stock |
| 100mg | $1350 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-101922 |
| M.Wt: | 337.42 |
| Formula: | C19H23N5O |
| Purity: | >98 % |
| Solubility: | DMSO : 14.29 mg/mL (ultrasonic) |
IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM. IC50 & Target: IC50: 7 nM (IRAK4)[1] In Vitro: The in vitro metabolic stability profiles of IRAK4-IN-1 (Compound 23) is measured, with EC50 of 2300 nM for the rat whole blood (RWB) [1]. In Vivo: Oral pharmacokinetic studies of IRAK4-IN-1 (Compound 23) show it to have high bioavailability of 73% and low plasma clearance (Clp=22 mL/min/kg) leading to a reasonable half-life of 1.3 h[1].
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- IRAK4-IN-1
- Cat. No.:
- HY-101922
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