UNC4203


CAS No. : 1818234-19-3

1818234-19-3
Price and Availability of CAS No. : 1818234-19-3
Size Price Stock
5mg $140 In-stock
10mg $225 In-stock
25mg $450 In-stock
50mg $730 In-stock
100mg $1180 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-124502
M.Wt: 504.71
Formula: C30H44N6O
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 1818234-19-3 :

UNC4203 is a potent, orally available and highly selective MERTK inhibitor, with IC50s of 1.2 nM, 140 nM, 42 nM and 90 nM for MERTK, AXL, TYRO3 and FLT3, respectively[1]. In Vivo: Mice are treated with UNC4203 (compound 24) at a dose of 10 mg/kg administered via oral (po) or iv routes. Under the condition, UNC4203 (compound 24) has 58% oral bioavailability with a 7.8 h half-life, 1.7 L/kg volume of distribution, and 36 mL/min/kg clearance[1].

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