(5Z,2E)-CU-3
CAS No. : 1815598-71-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $120 | In-stock |
| 10mg | $210 | In-stock |
| 25mg | $460 | In-stock |
| 50mg | $780 | In-stock |
| 100mg | $1200 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-121638A |
| M.Wt: | 392.47 |
| Formula: | C16H12N2O4S3 |
| Purity: | >98 % |
| Solubility: | DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C) |
(5Z,2E)-CU-3 is a potent and selective inhibitor against the α-isozyme of DGK with an IC50 value of 0.6 μM, competitively inhibits the affinity of DGKα for ATP with a Km value of 0.48 mM. (5Z,2E)-CU-3 targets the catalytic region, but not the regulatory region of DGKα. (5Z,2E)-CU-3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells[1]. IC50 & Target:IC50: 0.6 μM (DGKα)[1]
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