Butamirate


CAS No. : 18109-80-3

18109-80-3
Price and Availability of CAS No. : 18109-80-3
Size Price Stock
5mg $50 In-stock
10mg $80 In-stock
25mg $150 In-stock
50 mg Get quote
100 mg Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-118545
M.Wt: 307.43
Formula: C18H29NO3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 18109-80-3 :

Butamirate is an orally active antitussive agent that acts centrally through the receptors in the brainstem. Butamirate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect. Butamirate inhibits glioblastoma (GBM) growth and STAT3 activity. Butamirate can be used for the study of glioblastoma[1][2]. In Vitro:Butamirate (0.01-10 μM; 7 days) could effectively suppress sphere formation and STAT3 activity[2].
Butamirate effectively inhibits interactions of RRAD with pSTAT3[2].
Butamirate shows decreased EGFR, STAT3, ERK and AKT phosphorylation in U87MG[2].
In Vivo:Butamirate (2 mg/kg; intraperitoneal administration) suppresses tumor growth in a glioblastoma xenograft mouse model without significant adverse effects[2].

Your information is safe with us.