GGTI-297
CAS No. : 181045-83-0
| Size | Price | Stock |
|---|---|---|
| 100 mg | Get quote | |
| 250 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-120271 |
| M.Wt: | 465.61 |
| Formula: | C26H31N3O3S |
| Purity: | >98 % |
| Solubility: |
GGTI-297 is a geranylgeranyl transferase I (GGTase-1) inhibitor with IC50 values of 56 nM and 203 nM for GGTase-1 and fanesyl transferase (FTase), respectively. GGTI-297 inhibits the processing of the geranylgeranylated protein Rap1A without affecting the farnesylated protein H-Ras[1][2].
In Vivo:GGTI-297 (70 mg/kg; ip; once a day; for 5-7 weeks) inhibits the growth in nude mice of A-549 and Calu-1 xenografts, both of which express K-Ras mutations[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- GGTI-297
- Cat. No.:
- HY-120271
- Quantity:
Your information is safe with us.