DT-061


CAS No. : 1809427-19-7

1809427-19-7
Price and Availability of CAS No. : 1809427-19-7
Size Price Stock
1mg $166 In-stock
5mg $350 In-stock
10mg $550 In-stock
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Cat. No. : HY-112929
M.Wt: 520.52
Formula: C25H23F3N2O5S
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 1809427-19-7 :

DT-061 is an orally bioavailable activator of protein phosphatase 2A (PP2A) and could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis[1]. IC50 & Target: PP2A[1]. In Vivo: DT-061 (5 mg/kg, oral gavage, 4 weeks) shows single-agent activity in inhibiting H358 or H441 xenograft growth. Additionally, the combination of DT-061 and AZD6244 is more significantly efficient[1].

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