SMAP-2
CAS No. : 1809068-70-9
(Synonyms: DT-1154)
| Size | Price | Stock |
|---|---|---|
| 5mg | $550 | In-stock |
| 10mg | $890 | In-stock |
| 50mg | $2850 | In-stock |
| 100mg | $4560 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-120272 |
| M.Wt: | 532.57 |
| Formula: | C27H27F3N2O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 300 mg/mL (ultrasonic) |
SMAP-2 (DT-1154) is an orally active protein phosphatase 2A (PP2A) activator, with anti-cancer activity[1][2].
IC50 & Target: PP2A[1]
In Vitro: SMAP-2 reduces cell viability of pancreatic ductal adenocarcinoma (PDA) cell lines in a dose-dependent manner[2].
In Vivo: SMAP-2 significantly reduces abdominal aortic aneurysms (AAA) incidence and aortic dilation in pro-AAA apolipoprotein E-null (ApoE-/-) mice[2].
SMAP-2 (15 mg/kg; i.g.; daily; 6 days a week; for approximately 14 days) has anti-tumor activity in pancreatic cancer mice model[2].
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