TIP48/49-IN-1


CAS No. : 1807337-58-1

1807337-58-1
Price and Availability of CAS No. : 1807337-58-1
Size Price Stock
1mg $680 In-stock
5mg $1715 In-stock
10mg $2570 In-stock
25mg $4360 In-stock
50mg $5660 In-stock
100mg $7300 In-stock
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Cat. No. : HY-103702
M.Wt: 536.02
Formula: C28H30ClN5O4
Purity: >98 %
Solubility:
Introduction of 1807337-58-1 :

TIP48/49-IN-1 (Compound B) is an orally active and specific inhibitor of RUVBL1/2 ATPase, with an IC50 of 59 nM for purified RUVBL1/2. TIP48/49-IN-1 affects DNA replication process, and leads to S-phase arrest. TIP48/49-IN-1 induces apoptosis. TIP48/49-IN-1 inhibits tumor growth and radiosensitizes non-small cell lung cancer cells (NSCLC)[1].

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