Fentiazac


CAS No. : 18046-21-4

18046-21-4
Price and Availability of CAS No. : 18046-21-4
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Cat. No. : HY-118752
M.Wt: 329.81
Formula: C17H12ClNO2S
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 18046-21-4 :

Fentiazac, alkanoic acid derivative, is an orally active non-steroidal anti-inflammatory agent, with analgesic, antipyretic and platelet anti-aggregation activity. Fentiazac can be used to research inflammatory diseases such as rheumatoid arthritis, osteoarthritis and tendinitis[1][2][3]. In Vivo:Fentiazac is well tolerated after repeated oral administration in rats, monkeys and dogs; and no significant modifications in the heart and bone marrow function, as well as blood chemistry[1].
Tolerance of Fentiazac in rat, monkey and dog[1].
Species Tolerant dosage Tolerant administration day
Rat 0-50 mg/kg/day 90 days
Red pated monkey 40 mg/kg/day 90 days
0-30 mg/kg/day 180 days
African green monkey 0-8 mg/kg/day 79 to 93 days
dog 16.6 mg/kg/day 180 days

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