Repotrectinib (Standard)
CAS No. : 1802220-02-5
(Synonyms: TPX-0005 (Standard); Ropotrectinib (Standard))
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| Cat. No. : | HY-103022R |
| M.Wt: | 355.37 |
| Formula: | C18H18FN5O2 |
| Purity: | >98 % |
| Solubility: |
Repotrectinib (Standard) is the analytical standard of Repotrectinib (HY-103022). This product is intended for research and analytical applications. Repotrectinib (TPX-0005) is a potent ROS1 (IC50=0.07 nM) and TRK (IC50=0.83/0.05/0.1 nM for TRKA/B/C) inhibitor. Repotrectinib potently inhibits WT ALK (IC50=1.01 nM). Repotrectinib has anti-cancer activity[1][2]. IC50 & Target:IC50: 0.07 nM (ROS1), 0.83/0.05/0.1 nM (TRKA/B/C), 1.01 nM (ALK), 1.04 nM (JAK2), 1.66 nM (LYN), 5.3 nM (Src), 6.96 nM (FAK)[1][2]
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- Repotrectinib (Standard)
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