SR121566A
CAS No. : 180144-61-0
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| Cat. No. : | HY-U00235 |
| M.Wt: | 431.51 |
| Formula: | C20H25N5O4S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
SR121566A is a novel non-peptide Glycoprotein IIb/IIIa (GP IIb-IIIa) antagonist, which can inhibit ADP-, arachidonic acid- and collagen-induced human platelet aggregation with IC50s of 46±7.5, 56±6 and 42±3 nM, respectively. IC50 & Target: GP IIb-IIIa[1] In Vivo: SR121566A leads to dose-dependent increases in TTO, a statistically significant increase being observed at the doses of 0.3 mg/kg (473%) and 30 mg/kg (771%), respectively[2].
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