LEI105
CAS No. : 1800327-36-9
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| Cat. No. : | HY-112828 |
| M.Wt: | 384.47 |
| Formula: | C25H24N2O2 |
| Purity: | >98 % |
| Solubility: |
LEI105 is a potent, highly selective and reversible dual diacylglycerol lipase (DAGL)-α/DAGL-β inhibitor. LEI105 reduces 2-arachidonoylglycerol levels in Neuro2A cells. LEI105 also reduces cannabinoid CB1-receptor-mediated short-term synaptic plasticity in a mouse hippocampal slice model. LEI105 is promising for research of diseases, such as obesity, related metabolic disorders and neuroinflammation[1].
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