7-Chlorokynurenic acid
CAS No. : 18000-24-3
(Synonyms: 7-CKA)
| Size | Price | Stock |
|---|---|---|
| 100mg | $53 | In-stock |
| 250mg | $88 | In-stock |
| 1g | $238 | In-stock |
| 5g | $800 | In-stock |
| 10 g | Get quote | |
| 50 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-100811 |
| M.Wt: | 223.61 |
| Formula: | C10H6ClNO3 |
| Purity: | >98 % |
| Solubility: | DMSO : 14.29 mg/mL (ultrasonic);H2O : < 0.1 mg/mL |
7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery[1][2].
IC50 & Target: Ki: 0.59 μM (reuptake of glutamate)[1]
IC50: 0.56 μM (Glycine B coagonist site of NMDA receptor)[2]
In Vivo: Male Sprague-Dawley rats pretreated with 7-Chlorokynurenic acid (10 nM) shows a significant retardation of development of both the electroencephalographic and motor (17.7±2.9 daily stimulations) components of the seizure response[3].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- 7-Chlorokynurenic acid
- Cat. No.:
- HY-100811
- Quantity:
Your information is safe with us.