MMAF (sodium)
CAS No. : 1799706-65-2
(Synonyms: Monomethylauristatin F (sodium))
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $70 | In-stock |
| 25mg | $114 | In-stock |
| 50mg | $160 | In-stock |
| 100mg | $240 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-15579B |
| M.Wt: | 753.94 |
| Formula: | C39H64N5NaO8 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 200 mg/mL |
MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A[1][2][3]. In Vitro: MMAF inhibits anaplastic large cell lymphoma Karpas 299, breast carcinoma H3396, renal cell carcinoma 786-O and Caki-1 cells with IC50s of 119, 105, 257 and 200 nM in vitro cytotoxicity assay[4].
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