OAT-177
CAS No. : 1799548-33-6
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| Cat. No. : | HY-120107 |
| M.Wt: | 376.93 |
| Formula: | C19H29ClN6 |
| Purity: | >98 % |
| Solubility: |
OAT-177 is a potent dual inhibitor targeting acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT1) with an IC50=14.2 nM for human AMCase and IC50=232 nM for human CHIT1. OAT-177 is promising for research of chronic inflammatory and fibrotic-related lung diseases such as asthma and idiopathic pulmonary fibrosis[1].
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