sn-Glycerol 3-phosphate
CAS No. : 17989-41-2
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| Cat. No. : | HY-113128 |
| M.Wt: | 172.07 |
| Formula: | C3H9O6P |
| Purity: | >98 % |
| Solubility: | H2O : 125 mg/mL (ultrasonic) |
sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism[1][2]. In Vitro:The cytosolic GPDH consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP), and the resulting sn-Glycerol 3-phosphate passes through the permeable mitochondrial outer membrane. sn-Glycerol 3-phosphate is reoxidized to DHAP at the outer surface of the inner mitochondrial membrane by the mitochondrial FAD-GPDH, which donates the electrons to the mitochondrial ubiquinone pool. The DHAP is subsequently channeled back to the cytosolic compartment[2].
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